cefapirin


SMILES CC(=O)OCC1=C(N2[C@H](SC1)[C@H](NC(=O)CSC1=CC=NC=C1)C2=O)C(O)=O
InChIKey UQLLWWBDSUHNEB-CZUORRHYSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 423.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pIC50 8.26 8.26 8.26 Drug Central
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pIC50 8.32 8.32 8.32 Drug Central
α2C ADA2C Human Adrenoceptors A pIC50 8.33 8.33 8.33 Drug Central
D2 DRD2 Human Dopamine A pIC50 8.33 8.33 8.33 Drug Central
D4 DRD4 Human Dopamine A pIC50 8.3 8.3 8.3 Drug Central
H2 HRH2 Human Histamine A pIC50 8.28 8.28 8.28 Drug Central
δ OPRD Human Opioid A pIC50 8.3 8.3 8.3 Drug Central
κ OPRK Human Opioid A pIC50 8.28 8.28 8.28 Drug Central
μ OPRM Human Opioid A pIC50 8.27 8.27 8.27 Drug Central
SST4 SSR4 Human Somatostatin A pIC50 8.29 8.29 8.29 Drug Central
NK1 NK1R Human Tachykinin A pIC50 8.31 8.31 8.31 Drug Central
CB1 CNR1 Human Cannabinoid A pIC50 8.39 8.39 8.39 Drug Central
D3 DRD3 Human Dopamine A pIC50 8.34 8.34 8.34 Drug Central
NK2 NK2R Human Tachykinin A pIC50 8.31 8.31 8.31 Drug Central