CHEMBL1223748


SMILES COc1ccccc1N1CCN(CCCCNc2nccc3ccccc23)CC1
InChIKey GVOWTPVTYQMHDU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 390.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKi 7.29 7.29 7.29 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.16 8.08 9.0 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 8.22 8.22 8.22 ChEMBL
D2 DRD2 Human Dopamine A pKi 9.0 9.0 9.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database