ACRIVASTINE


SMILES Cc1ccc(/C(=C\CN2CCCC2)c2cccc(/C=C/C(=O)O)n2)cc1
InChIKey PWACSDKDOHSSQD-IUTFFREVSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 348.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Ligand site mutations H1

Sankey plot

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Guinea pig Histamine A pIC50 5.21 5.21 5.21 ChEMBL
H1 HRH1 Human Histamine A pIC50 8.15 8.15 8.15 Drug Central
H1 HRH1 Guinea pig Histamine A pIC50 8.28 8.28 8.28 Drug Central