CHEMBL1241913


SMILES Cc1ccc2c(N3CCN(CCc4cccc5c4OCc4c(C(N)=O)ncn4-5)CC3)cccc2n1
InChIKey HLQJZFFWUXHYMB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 468.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Rat 5-Hydroxytryptamine A pKi 8.49 8.49 8.49 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 8.8 8.95 9.1 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKd 8.93 8.93 8.93 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 9.8 9.9 10.0 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKd 9.77 9.77 9.77 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 8.56 8.56 8.56 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 10.16 10.16 10.16 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 9.5 9.72 9.94 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKd 9.69 9.69 9.69 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database