CHEMBL1242725


SMILES COc1ccccc1N1CCN(C[C@@H]2CO[C@@](CN3C(=O)CCC3=O)(c3ccccc3)O2)CC1
InChIKey JCZSBAKXMUXIIN-QFQXNSOFSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 465.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 6.65 6.65 6.65 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 7.79 7.79 7.79 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 7.39 7.39 7.39 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.59 7.59 7.59 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database