GPCRdb

LUF5981

Agent/drug
Bioactivity

LUF5981

SMILES	c1ccc(-c2cc(-c3ccccc3)c3nc(C4CCCCC4)[nH]c3n2)cc1
InChIKey	DXBBMCIVYYJMJC-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	2
Hydrogen bond donors	1
Rotatable bonds	3
Molecular weight (Da)	353.2

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

A₁	AA1R	Human	Adenosine	A	pKi	9.05	9.05	9.05	Guide to Pharmacology
A₁	AA1R	Human	Adenosine	A	pKi	9.05	9.05	9.05	ChEMBL
A_2A	AA2AR	Human	Adenosine	A	pKi	6.71	6.71	6.71	Guide to Pharmacology
A_2A	AA2AR	Human	Adenosine	A	pKi	6.71	6.71	6.71	ChEMBL
A_2B	AA2BR	Human	Adenosine	A	pKi	6.52	6.52	6.52	Guide to Pharmacology
A_2B	AA2BR	Human	Adenosine	A	pKi	6.52	6.52	6.52	ChEMBL
A₃	AA3R	Human	Adenosine	A	pKi	6.20	6.20	6.20	Guide to Pharmacology
A₃	AA3R	Human	Adenosine	A	pKi	6.20	6.20	6.20	ChEMBL

Showing 1 to 8 of 8 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

A₁	AA1R	Human	Adenosine	A	pIC50	5.77	5.77	5.77	ChEMBL

Showing 1 to 1 of 1 entry

LUF5981

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids GPCRdb

Compound is not listed as a drug.