CHEMBL1258671


SMILES CCCCN1CCC(COC(=O)c2cc(F)c(N)c3c2OCCO3)CC1
InChIKey WLHFUBIRAHRPHA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 366.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 6.5 6.5 6.5 ChEMBL
5-HT4 5HT4R Human 5-Hydroxytryptamine A pKi 8.68 8.68 8.68 ChEMBL
5-HT4 5HT4R Guinea pig 5-Hydroxytryptamine A pKi 9.48 9.48 9.48 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 5.54 5.54 5.54 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 5.04 5.04 5.04 ChEMBL
α2B ADA2B Human Adrenoceptors A pKi 6.11 6.11 6.11 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.23 6.23 6.23 ChEMBL
D2 DRD2 Rat Dopamine A pKi 6.21 6.21 6.21 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 7.06 7.06 7.06 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.78 6.78 6.78 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.08 5.08 5.08 ChEMBL
H3 HRH3 Guinea pig Histamine A pKi 5.3 5.3 5.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT4 5HT4R Human 5-Hydroxytryptamine A pEC50 8.23 8.23 8.23 ChEMBL