macitentan
macitentan
| SMILES | CCCNS(=O)(=O)Nc1ncnc(OCCOc2ncc(Br)cn2)c1-c1ccc(Br)cc1 |
| InChIKey | JGCMEBMXRHSZKX-UHFFFAOYSA-N |
Chemical Properties
| Hydrogen bond acceptors | 8 |
| Hydrogen bond donors | 2 |
| Rotatable bonds | 11 |
| Molecular weight (Da) | 586.0 |
Database connections
| Structure pdb | 8XVJ |
No bioactivity data available.
macitentan
Drug properties
| Molecular type | Small molecule |
| Physiological/Surrogate | Surrogate |
| Approved drug | Yes |
Clinical Trials
Phase I
2
Phase II
4
Phase III
5
Approved
Yes
Database connections
| Structure pdb | 8XVJ |
Sankey plot
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Drug Information
| Target | Disease | Phase | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Gene | Protein | Receptor family | Ligand type | Class | Indication name | ICD11 | ATC | Association score | Phase | Approved |