mavorixafor
mavorixafor
SMILES | NCCCCN([C@H]1CCCc2c1nccc2)Cc1nc2c([nH]1)cccc2 |
InChIKey | WVLHHLRVNDMIAR-IBGZPJMESA-N |
Chemical Properties
Hydrogen bond acceptors | 4 |
Hydrogen bond donors | 2 |
Rotatable bonds | 7 |
Molecular weight (Da) | 349.2 |
Database connections
Ligand site mutations | CXCR4 |
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
Protein | Gene | Species | Family | Class | Type | Min | Avg | Max | Database |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
Protein | Gene | Species | Family | Class | Type | Min | Avg | Max | Database |
mavorixafor
Drug properties
Molecular type | Small molecule |
Physiological/Surrogate | Surrogate |
Approved drug | Yes |
Clinical Trials
Phase I
7
Phase II
1
Phase III
0
Approved
Yes
Database connections
Ligand site mutations | CXCR4 |
Sankey plot
Drug Information
Target | Disease | Phase | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Gene | Protein | Receptor family | Ligand type | Class | Indication name | ICD11 | ATC | Association score | Phase | Approved |