CHEMBL1259172


SMILES NCc1ccc2c(c1)c(C1CCN(CCN3CCNC3=O)CC1)cn2-c1ccc(F)cc1
InChIKey PBYSLXLVOFLVAY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 435.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Golden hamster Adrenoceptors A pKi 8.96 8.96 8.96 ChEMBL
α1A ADA1A Bovine Adrenoceptors A pKi 9.74 9.74 9.74 ChEMBL
α1D ADA1D Rat Adrenoceptors A pKi 9.16 9.16 9.16 ChEMBL
H1 HRH1 Human Histamine A pKi 7.19 7.19 7.19 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.43 7.43 7.43 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.66 7.66 7.66 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database