CHEMBL126340


SMILES CN(C)CCc1cccc2c1cc(C(=O)c1ccccc1)n2S(=O)(=O)c1ccccc1
InChIKey PBBGIYKMAVNTAL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 432.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT5A 5HT5A Rat 5-Hydroxytryptamine A pKi 5.8 5.8 5.8 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 6.72 6.72 6.72 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 7.01 7.01 7.01 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.89 5.89 5.89 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 8.52 8.52 8.52 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.18 7.18 7.18 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.32 6.32 6.32 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.12 6.12 6.12 ChEMBL
5-HT1F 5HT1F Human 5-Hydroxytryptamine A pKi 6.24 6.24 6.24 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database