GPCRdb

mescaline

Agent/drug
Bioactivity

mescaline

SMILES	COc1cc(CCN)cc(OC)c1OC
InChIKey	RHCSKNNOAZULRK-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	1
Rotatable bonds	5
Molecular weight (Da)	211.1

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids GPCRdb
Ligand site mutations	5-HT_2A

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Rat	5-Hydroxytryptamine	A	pKi	5.16	5.16	5.16	ChEMBL
5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pKi	5.34	5.34	5.34	PDSP Ki database
5-HT_2A	5HT2A	Human	5-Hydroxytryptamine	A	pKi	5.20	5.20	5.20	PDSP Ki database
5-HT_2A	5HT2A	Human	5-Hydroxytryptamine	A	pKi	6.26	6.26	6.26	ChEMBL
5-HT_2B	5HT2B	Human	5-Hydroxytryptamine	A	pKi	6.10	6.10	6.10	ChEMBL
5-HT_2B	F6QI78	Bovine	5-Hydroxytryptamine	A	pKi	5.00	5.00	5.00	PDSP Ki database
5-HT_2C	5HT2C	Rat	5-Hydroxytryptamine	A	pKi	6.42	6.42	6.42	ChEMBL
5-HT_2C	5HT2C	Human	5-Hydroxytryptamine	A	pKi	6.52	6.52	6.52	ChEMBL
5-HT_2C	5HT2C	Human	5-Hydroxytryptamine	A	pKi	4.77	4.77	4.77	PDSP Ki database

Showing 1 to 9 of 9 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_2A	5HT2A	Human	5-Hydroxytryptamine	A	pEC50	5.59	5.59	5.59	Guide to Pharmacology
5-HT_2C	5HT2C	Rat	5-Hydroxytryptamine	A	pEC50	4.62	4.62	4.62	ChEMBL

Showing 1 to 2 of 2 entries

mescaline

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids GPCRdb
Ligand site mutations	5-HT_2A

Compound is not listed as a drug.