VUF-5296


SMILES N[C@@H]1C[C@H]1c1c[nH]cn1
InChIKey OWWNABDDYQLERE-RFZPGFLSSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 1
Molecular weight (Da) 123.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Rat Histamine A pKi 7.38 7.83 8.5 ChEMBL
H3 HRH3 Human Histamine A pKi 7.17 7.17 7.17 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H2 HRH2 Human Histamine A pEC50 5.6 5.6 5.6 ChEMBL
H3 HRH3 Human Histamine A pEC50 6.14 6.69 7.24 ChEMBL