PIPERTRAMINE AMIDE


SMILES COc1ccccc1CN1CCC(C2CCN(C(=O)CCCCCCC(=O)N3CCC(C4CCN(Cc5ccccc5OC)CC4)CC3)CC2)CC1
InChIKey UWKMFEOQWPCWLU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 15
Molecular weight (Da) 714.5

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 6.74 6.74 6.74 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 7.78 7.78 7.78 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 7.01 7.01 7.01 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 8.04 8.04 8.04 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 6.97 6.97 6.97 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database