ONO-4057


SMILES COc1ccc(cc1)/C=C/CCCCOc1cccc(c1CCC(=O)O)OCCCCC(=O)O
InChIKey JOPSSWGWLCLPPF-RUDMXATFSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 17
Molecular weight (Da) 470.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
BLT1 LT4R1 Human Leukotriene A pKi 8.43 8.43 8.43 Guide to Pharmacology
BLT1 LT4R1 Human Leukotriene A pKi 8.4 8.41 8.43 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
BLT1 LT4R1 Human Leukotriene A pIC50 5.52 5.83 6.15 Guide to Pharmacology