GPCRdb

octreotide

Agent/drug
Bioactivity

octreotide

SMILES	None
InChIKey	DEQANNDTNATYII-UHFFFAOYSA-N
Sequence	FCFWKTCT

Chemical Properties

Hydrogen bond acceptors	None
Hydrogen bond donors	None
Rotatable bonds	None
Molecular weight (Da)

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids DrugBank ChEMBL_compound_ids PubChem PubChem PubChem GPCRdb

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

μ	OPRM	Human	Opioid	A	pKi	7.92	7.92	7.92	PDSP Ki database
μ	OPRM	Human	Opioid	A	pKi	8.10	8.10	8.10	Drug Central
SST1	SSR1	Human	Somatostatin	A	pKi	5.92	6.29	6.65	PDSP Ki database
SST1	SSR1	Human	Somatostatin	A	pKi	8.18	8.18	8.18	Drug Central
SST2	SSR2	Human	Somatostatin	A	pKi	8.70	9.30	9.90	Guide to Pharmacology
SST2	SSR2	Rat	Somatostatin	A	pKi	8.70	8.70	8.70	Guide to Pharmacology
SST2	SSR2	Mouse	Somatostatin	A	pKi	7.50	8.35	9.20	Guide to Pharmacology
SST2	SSR2	Human	Somatostatin	A	pKi	9.40	9.40	9.40	ChEMBL
SST2	SSR2	Human	Somatostatin	A	pKi	8.57	9.24	9.92	PDSP Ki database
SST2	SSR2	Mouse	Somatostatin	A	pKi	7.46	8.65	9.30	PDSP Ki database
SST2	SSR2	Rat	Somatostatin	A	pKi	8.70	8.70	8.70	PDSP Ki database
SST2	SSR2	Rat	Somatostatin	A	pKi	8.06	8.06	8.06	Drug Central
SST3	SSR3	Human	Somatostatin	A	pKi	7.40	8.00	8.60	Guide to Pharmacology
SST3	SSR3	Rat	Somatostatin	A	pKi	7.80	7.80	7.80	Guide to Pharmacology
SST3	SSR3	Human	Somatostatin	A	pKi	6.82	7.99	8.60	PDSP Ki database
SST3	SSR3	Mouse	Somatostatin	A	pKi	6.82	7.95	8.52	PDSP Ki database
SST3	SSR3	Rat	Somatostatin	A	pKi	7.85	7.85	7.85	PDSP Ki database
SST3	SSR3	Human	Somatostatin	A	pKi	8.08	8.08	8.08	Drug Central
SST3	SSR3	Rat	Somatostatin	A	pKi	8.11	8.11	8.11	Drug Central
SST4	SSR4	Human	Somatostatin	A	pKi	7.18	7.18	7.18	ChEMBL

Showing 1 to 20 of 30 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

SST2	SSR2	Human	Somatostatin	A	pEC50	10.52	10.52	10.52	ChEMBL
SST2	SSR2	Human	Somatostatin	A	pEC50	7.97	7.97	7.97	Drug Central
SST2	SSR2	Mouse	Somatostatin	A	pIC50	8.02	8.02	8.02	Drug Central
SST3	SSR3	Mouse	Somatostatin	A	pIC50	8.50	8.50	8.50	Guide to Pharmacology
SST3	SSR3	Mouse	Somatostatin	A	pIC50	8.07	8.07	8.07	Drug Central
SST5	SSR5	Human	Somatostatin	A	pIC50	8.07	8.07	8.07	Drug Central
SST5	SSR5	Rat	Somatostatin	A	pIC50	8.05	8.05	8.05	Drug Central
SST5	SSR5	Human	Somatostatin	A	pIC50	7.66	7.66	7.66	ChEMBL

Showing 1 to 8 of 8 entries

octreotide

Drug properties

Molecular type	Peptide
Physiological/Surrogate	Surrogate
Approved drug	Yes

Clinical Trials

Phase I 10

Phase II 70

Phase III 20

Approved Yes

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids DrugBank ChEMBL_compound_ids PubChem PubChem PubChem GPCRdb

Sankey plot

Drug Information

Search:

Target					Disease				Phase

Gene	Protein	Receptor family	Ligand type	Class	Indication name	ICD11	ATC	Association score	Phase	Approved

SSR1	SST1 receptor	Somatostatin receptors	Peptide receptors	Class A	Acromegaly or pituitary gigantism	5A60.0	H01C	0.604	4	Yes
SSR1	SST1 receptor	Somatostatin receptors	Peptide receptors	Class A	Autosomal dominant polycystic kidney disease	GB81	H01C	0.332	3	Yes
SSR1	SST1 receptor	Somatostatin receptors	Peptide receptors	Class A	Benign neoplasm of endocrine pancreas	2E92.9	H01C	0.085	2	Yes
SSR1	SST1 receptor	Somatostatin receptors	Peptide receptors	Class A	Constipation	ME05.0	H01C	0.396	2	Yes
SSR1	SST1 receptor	Somatostatin receptors	Peptide receptors	Class A	Diabetic retinopathy, unspecified	9B71.0Z	H01C	0.390	3	Yes
SSR1	SST1 receptor	Somatostatin receptors	Peptide receptors	Class A	Diarrhoea	ME05.1	H01C	0.391	4	Yes
SSR1	SST1 receptor	Somatostatin receptors	Peptide receptors	Class A	Gastrointestinal bleeding, unspecified	ME24.9Z	H01C	0.037	1	Yes
SSR1	SST1 receptor	Somatostatin receptors	Peptide receptors	Class A	Hepatocellular carcinoma of liver	2C12.02	H01C	0.372	3	Yes
SSR1	SST1 receptor	Somatostatin receptors	Peptide receptors	Class A	Idiopathic pulmonary fibrosis	CB03.4	H01C	0.037	2	Yes
SSR1	SST1 receptor	Somatostatin receptors	Peptide receptors	Class A	Irritable bowel syndrome, type unspecified	DD91.0Z	H01C	0.037	1	Yes
SSR1	SST1 receptor	Somatostatin receptors	Peptide receptors	Class A	Kidney failure, unspecified	GB6Z	H01C	0.092	2	Yes
SSR1	SST1 receptor	Somatostatin receptors	Peptide receptors	Class A	Malignant lymphoma, not elsewhere classified	2B33.5	H01C	0.092	2	Yes
SSR1	SST1 receptor	Somatostatin receptors	Peptide receptors	Class A	Malignant neoplasm of liver, unspecified	2C12.0Z	H01C	0.092	2	Yes
SSR1	SST1 receptor	Somatostatin receptors	Peptide receptors	Class A	Malignant neoplasms of prostate, unspecified	2C82.Z	H01C	0.101	2	Yes
SSR1	SST1 receptor	Somatostatin receptors	Peptide receptors	Class A	Meningiomas, unspecified	2A01.0Z	H01C	0.103	2	Yes
SSR1	SST1 receptor	Somatostatin receptors	Peptide receptors	Class A	Migraine, unspecified	8A80.Z	H01C	0.037	2	Yes
SSR1	SST1 receptor	Somatostatin receptors	Peptide receptors	Class A	Neoplasms of unknown behaviour of other specified respiratory organ, intrathoracic organ or middle ear	2F91.Y	H01C	0.092	2	Yes
SSR1	SST1 receptor	Somatostatin receptors	Peptide receptors	Class A	Obesity, unspecified	5B81.Z	H01C	0.512	2	Yes
SSR1	SST1 receptor	Somatostatin receptors	Peptide receptors	Class A	Other specified malignant neoplasms of thymus	2C27.Y	H01C	0.092	2	Yes
SSR1	SST1 receptor	Somatostatin receptors	Peptide receptors	Class A	Other specified malignant neoplasms of unspecified primary sites	2D4Y	H01C	0.365	3	Yes

Showing 1 to 20 of 105 entries

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octreotide

octreotide

Chemical Properties

Database connections

Bioactivities

octreotide

Drug properties

Clinical Trials

Database connections

Sankey plot

Drug Information