GPCRdb

olmesartan

Agent/drug
Bioactivity

olmesartan

SMILES	CCCc1nc(C(C)(C)O)c(C(=O)OCc2oc(=O)oc2C)n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1
InChIKey	UQGKUQLKSCSZGY-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	11
Hydrogen bond donors	2
Rotatable bonds	10
Molecular weight (Da)	558.2

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids DrugBank Drug Central PubChem GPCRdb

No bioactivity data available.

olmesartan

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	Yes

Distribution across phases (no. indications)

Phase I 0

Phase II 1

Phase III 5

Phase IV 5

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids DrugBank Drug Central PubChem GPCRdb

Sankey plot

Drug Information

Search:

Target					Disease

Gene	Protein	Receptor family	Ligand type	Class	Name	Phase	ICD11	ATC	Association score

AGTR1	AT₁ receptor	Angiotensin receptors	Peptide receptors	A	Acute myocardial infarction, unspecified	4	BA41.Z	C09D, C09C	0.474
AGTR1	AT₁ receptor	Angiotensin receptors	Peptide receptors	A	Atherosclerotic chronic arterial occlusive disease, unspecified	3	BD40.Z	C09D, C09C	0.207
AGTR1	AT₁ receptor	Angiotensin receptors	Peptide receptors	A	Chronic kidney disease, stage unspecified	3	GB61.Z	C09D, C09C	0.595
AGTR1	AT₁ receptor	Angiotensin receptors	Peptide receptors	A	Diseases of the urinary system, unspecified	3	GC2Z	C09D, C09C	0.317
AGTR1	AT₁ receptor	Angiotensin receptors	Peptide receptors	A	Essential hypertension, unspecified	4	BA00.Z	C09D, C09C	0.708
AGTR1	AT₁ receptor	Angiotensin receptors	Peptide receptors	A	Heart failure, unspecified	4	BD1Z	C09D, C09C	0.611
AGTR1	AT₁ receptor	Angiotensin receptors	Peptide receptors	A	Nephritic syndrome	2	GB40	C09D, C09C	0.366
AGTR1	AT₁ receptor	Angiotensin receptors	Peptide receptors	A	Proteinuria, unspecified	3	MF96.Z	C09D, C09C	0.507
AGTR1	AT₁ receptor	Angiotensin receptors	Peptide receptors	A	Stroke not known if ischaemic or haemorrhagic	4	8B20	C09D, C09C	0.605

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