GPCRdb

PPADS

Agent/drug
Bioactivity

PPADS

SMILES	Cc1nc(/N=N/c2ccc(S(=O)(=O)O)cc2S(=O)(=O)O)c(COP(=O)(O)O)c(C=O)c1O
InChIKey	PNFZSRRRZNXSMF-WUKNDPDISA-N

Chemical Properties

Hydrogen bond acceptors	11
Hydrogen bond donors	5
Rotatable bonds	8
Molecular weight (Da)	511.0

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids ChEMBL_compound_ids GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

P2Y₁	P2RY1	Human	P2Y	A	pKi	5.20	5.20	5.20	Guide to Pharmacology

Showing 1 to 1 of 1 entry

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

P2Y₁	P2RY1	Human	P2Y	A	pEC50	4.74	5.37	6.00	ChEMBL
P2Y₁	P2RY1	Wild turkey	P2Y	A	pIC50	4.78	4.78	4.78	ChEMBL
P2Y₁₃	P2Y13	Human	P2Y	A	pIC50	4.90	4.90	4.90	Guide to Pharmacology
P2Y₁₃	P2Y13	Human	P2Y	A	pIC50	4.94	4.94	4.94	ChEMBL
P2Y₄	P2RY4	Human	P2Y	A	pEC50	2.00	3.50	5.00	Guide to Pharmacology
P2Y₆	P2RY6	Human	P2Y	A	pKB	4.00	4.00	4.00	Guide to Pharmacology
TSH	TSHR	Human	Glycoprotein hormone	A	Potency	5.50	5.50	5.50	ChEMBL

Showing 1 to 7 of 7 entries

PPADS

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Clinical Trials

Phase I 0

Phase II 0

Phase III 0

Approved No

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids ChEMBL_compound_ids GPCRdb

Compound is not listed as a drug.