rivenprost


SMILES COCc1cccc(c1)C[C@@H](/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1CCSCCCC(=O)OC)O
InChIKey FBQUXLIJKPWCAO-AZIFJQEOSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 13
Molecular weight (Da) 450.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP3 PE2R3 Mouse Prostanoid A pKi 7.25 7.25 7.25 ChEMBL
EP3 PE2R3 Mouse Prostanoid A pKi 7.25 7.25 7.25 Guide to Pharmacology
EP4 PE2R4 Mouse Prostanoid A pKi 9.2 9.2 9.2 Guide to Pharmacology
EP2 PE2R2 Mouse Prostanoid A pKi 6.2 6.2 6.2 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP4 PE2R4 Mouse Prostanoid A pEC50 8.8 8.8 8.8 ChEMBL