GPCRdb

RU 24969

Agent/drug
Bioactivity

RU 24969

SMILES	COc1ccc2[nH]cc(C3=CCNCC3)c2c1
InChIKey	KRVMLPUDAOWOGN-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	2
Hydrogen bond donors	2
Rotatable bonds	2
Molecular weight (Da)	228.1

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pKi	9.00	9.00	9.00	Guide to Pharmacology
5-HT_1A	5HT1A	Rat	5-Hydroxytryptamine	A	pKi	7.96	8.04	8.30	ChEMBL
5-HT_1B	5HT1B	Human	5-Hydroxytryptamine	A	pKi	8.10	8.10	8.10	Guide to Pharmacology
5-HT_1B	5HT1B	Rat	5-Hydroxytryptamine	A	pKi	8.40	8.40	8.40	ChEMBL
5-HT_1D	5HT1D	Human	5-Hydroxytryptamine	A	pKi	7.70	7.70	7.70	Guide to Pharmacology
5-HT_2A	5HT2A	Human	5-Hydroxytryptamine	A	pKi	6.90	6.90	6.90	Guide to Pharmacology
5-HT_2B	5HT2B	Human	5-Hydroxytryptamine	A	pKi	6.90	6.90	6.90	Guide to Pharmacology
5-HT_2B	5HT2B	Rat	5-Hydroxytryptamine	A	pKi	7.80	7.80	7.80	Guide to Pharmacology
5-HT_2C	5HT2C	Human	5-Hydroxytryptamine	A	pKi	6.40	6.40	6.40	ChEMBL
5-HT_2C	5HT2C	Human	5-Hydroxytryptamine	A	pKi	6.80	6.80	6.80	Guide to Pharmacology
5-HT_5A	5HT5A	Human	5-Hydroxytryptamine	A	pKi	6.00	6.00	6.00	Guide to Pharmacology
5-HT_5A	5HT5A	Mouse	5-Hydroxytryptamine	A	pKi	6.50	6.50	6.50	Guide to Pharmacology
5-HT₆	5HT6R	Human	5-Hydroxytryptamine	A	pKi	6.20	6.20	6.20	Guide to Pharmacology
5-HT₇	5HT7R	Mouse	5-Hydroxytryptamine	A	pKi	6.90	6.90	6.90	Guide to Pharmacology

Showing 1 to 14 of 14 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Rat	5-Hydroxytryptamine	A	pIC50	7.85	8.12	8.40	ChEMBL
5-HT_1B	5HT1B	Rat	5-Hydroxytryptamine	A	pIC50	8.22	8.46	8.70	ChEMBL
5-HT_1D	5HT1D	Human	5-Hydroxytryptamine	A	pIC50	7.41	7.41	7.41	ChEMBL
5-HT_2C	5HT2C	Human	5-Hydroxytryptamine	A	pIC50	6.52	6.53	6.54	ChEMBL
5-HT₆	5HT6R	Human	5-Hydroxytryptamine	A	pIC50	7.10	7.10	7.10	ChEMBL

Showing 1 to 5 of 5 entries

RU 24969

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids GPCRdb

Compound is not listed as a drug.