GPCRdb

CHEMBL143272

Agent/drug
Bioactivity

CHEMBL143272

SMILES	CC(=O)N1CCC(=C2c3cc(F)ccc3CCc3cccnc32)CC1
InChIKey	ROTYCHLMKZTPEY-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	2
Hydrogen bond donors	0
Rotatable bonds	0
Molecular weight (Da)	336.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

H₁	HRH1	Rat	Histamine	A	pKi	5.54	5.54	5.54	ChEMBL

Showing 1 to 1 of 1 entry

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

PAF	PTAFR	Human	Platelet-activating factor	A	pIC50	6.09	6.09	6.09	ChEMBL

Showing 1 to 1 of 1 entry

CHEMBL143272

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.