GPCRdb

(S)-dimetindene

Agent/drug
Bioactivity

(S)-dimetindene

SMILES	C[C@@H](C1=C(CCN(C)C)Cc2ccccc21)c1ccccn1
InChIKey	MVMQESMQSYOVGV-OAHLLOKOSA-N

Chemical Properties

Hydrogen bond acceptors	2
Hydrogen bond donors	0
Rotatable bonds	5
Molecular weight (Da)	292.2

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

H₁	HRH1	Human	Histamine	A	pKi	7.16	7.16	7.16	Guide to Pharmacology
H₁	HRH1	Human	Histamine	A	pKi	7.16	7.16	7.16	ChEMBL
M₁	ACM1	Human	Acetylcholine (muscarinic)	A	pKi	6.72	6.72	6.72	Guide to Pharmacology
M₁	ACM1	Human	Acetylcholine (muscarinic)	A	pKi	6.72	6.72	6.72	ChEMBL
M₂	ACM2	Human	Acetylcholine (muscarinic)	A	pKi	7.52	7.52	7.52	ChEMBL
M₂	ACM2	Human	Acetylcholine (muscarinic)	A	pKi	7.52	7.52	7.52	Guide to Pharmacology
M₃	ACM3	Human	Acetylcholine (muscarinic)	A	pKi	6.86	6.86	6.86	Guide to Pharmacology
M₃	ACM3	Human	Acetylcholine (muscarinic)	A	pKi	6.86	6.86	6.86	ChEMBL
M₄	ACM4	Human	Acetylcholine (muscarinic)	A	pKi	6.53	6.53	6.53	Guide to Pharmacology
M₄	ACM4	Human	Acetylcholine (muscarinic)	A	pKi	6.53	6.53	6.53	ChEMBL
M₅	ACM5	Human	Acetylcholine (muscarinic)	A	pKi	6.12	6.12	6.12	Guide to Pharmacology
M₅	ACM5	Human	Acetylcholine (muscarinic)	A	pKi	6.12	6.12	6.12	ChEMBL

Showing 1 to 12 of 12 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

TSH	TSHR	Human	Glycoprotein hormone	A	Potency	4.40	4.40	4.40	ChEMBL

Showing 1 to 1 of 1 entry

(S)-dimetindene

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV 0

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids GPCRdb

Compound is not listed as a drug.