GPCRdb

CHEMBL144151

Agent/drug
Bioactivity

CHEMBL144151

SMILES	N[C@@](CC1c2ccccc2Oc2ccccc21)(C(=O)O)[C@H]1C[C@@H]1C(=O)O
InChIKey	VLZBRVJVCCNPRJ-ZQGRQUNCSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	3
Rotatable bonds	5
Molecular weight (Da)	353.1

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

mGlu₂	GRM2	Rat	Metabotropic glutamate	C	pKi	8.43	8.43	8.43	ChEMBL
mGlu₃	GRM3	Rat	Metabotropic glutamate	C	pKi	8.39	8.39	8.39	ChEMBL

Showing 1 to 2 of 2 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

mGlu₂	GRM2	Rat	Metabotropic glutamate	C	pEC50	7.30	7.30	7.30	ChEMBL
mGlu₂	GRM2	Human	Metabotropic glutamate	C	pIC50	6.70	6.70	6.70	ChEMBL
mGlu₃	GRM3	Human	Metabotropic glutamate	C	pIC50	7.80	7.80	7.80	ChEMBL
mGlu₃	GRM3	Rat	Metabotropic glutamate	C	pEC50	7.00	7.00	7.00	ChEMBL

Showing 1 to 4 of 4 entries

CHEMBL144151

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Clinical Trials

Phase I 0

Phase II 0

Phase III 0

Approved No

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.