CHEMBL138458


SMILES COC1Cc2ccccc2C2(CCN(CCCc3ccccc3)CC2)O1
InChIKey IJKYJDDNDXAREJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 351.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Human Histamine A pIC50 5.1 5.1 5.1 ChEMBL
D2 DRD2 Rat Dopamine A pIC50 5.8 5.8 5.8 ChEMBL
α2A ADA2A Human Adrenoceptors A pIC50 5.51 5.51 5.51 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 6.34 6.34 6.34 ChEMBL