GPCRdb

SR144528

Agent/drug
Bioactivity

SR144528

SMILES	Cc1ccc(Cn2nc(C(=O)N[C@@H]3C(C)(C)[C@@H]4CC[C@@]3(C)C4)cc2-c2ccc(Cl)c(C)c2)cc1
InChIKey	SUGVYNSRNKFXQM-XRHWURSXSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	1
Rotatable bonds	5
Molecular weight (Da)	475.2

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids GPCRdb
Ligand site mutations	CB₂

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

CB₁	CNR1	Human	Cannabinoid	A	pKi	5.25	6.53	8.70	ChEMBL
CB₂	CNR2	Human	Cannabinoid	A	pKi	8.30	8.75	9.20	Guide to Pharmacology
CB₂	CNR2	Human	Cannabinoid	A	pKi	6.93	8.38	9.51	ChEMBL

Showing 1 to 3 of 3 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

CB₁	CNR1	Human	Cannabinoid	A	pIC50	6.10	6.10	6.10	ChEMBL
CB₂	CNR2	Human	Cannabinoid	A	pEC50	4.57	6.28	7.63	ChEMBL
CB₂	CNR2	Human	Cannabinoid	A	pIC50	5.14	6.50	7.70	ChEMBL

Showing 1 to 3 of 3 entries

SR144528

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids GPCRdb
Ligand site mutations	CB₂

Compound is not listed as a drug.