GPCRdb

taranabant

Agent/drug
Bioactivity

taranabant

SMILES	C[C@H](NC(=O)C(C)(C)Oc1ccc(C(F)(F)F)cn1)[C@@H](Cc1ccc(Cl)cc1)c1cccc(C#N)c1
InChIKey	QLYKJCMUNUWAGO-GAJHUEQPSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	1
Rotatable bonds	8
Molecular weight (Da)	515.2

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids DrugBank GPCRdb
Structure pdb	5U09 9B9Y

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

CB₁	CNR1	Human	Cannabinoid	A	pKi	9.52	9.52	9.52	Guide to Pharmacology
CB₁	CNR1	Human	Cannabinoid	A	pKi	9.52	9.52	9.52	ChEMBL
CB₂	CNR2	Human	Cannabinoid	A	pKi	6.54	6.54	6.54	Guide to Pharmacology
CB₂	CNR2	Human	Cannabinoid	A	pKi	6.54	6.54	6.54	ChEMBL

Showing 1 to 4 of 4 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

CB₁	CNR1	Human	Cannabinoid	A	pIC50	7.66	9.15	10.03	ChEMBL
CB₁	CNR1	Human	Cannabinoid	A	pEC50	8.62	8.62	8.62	ChEMBL
CB₂	CNR2	Human	Cannabinoid	A	pIC50	5.93	6.39	6.54	ChEMBL

Showing 1 to 3 of 3 entries

taranabant

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	Yes

Clinical Trials

Phase I 0

Phase II 0

Phase III 0

Approved No

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids DrugBank GPCRdb
Structure pdb	5U09 9B9Y

Compound is not listed as a drug.