GPCRdb

TD-8954

Agent/drug
Bioactivity

TD-8954

SMILES	COC(=O)N1CCC(CN2CCC(CNC(=O)c3cccc4[nH]c(C(C)C)nc34)CC2)CC1
InChIKey	MZOITCJKGUIQEI-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	5
Hydrogen bond donors	2
Rotatable bonds	6
Molecular weight (Da)	455.3

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids DrugBank GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT₄	5HT4R	Human	5-Hydroxytryptamine	A	pKi	9.40	9.40	9.40	Guide to Pharmacology
5-HT₄	5HT4R	Human	5-Hydroxytryptamine	A	pKi	9.40	9.40	9.40	ChEMBL

Showing 1 to 2 of 2 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT₄	5HT4R	Human	5-Hydroxytryptamine	A	pEC50	8.82	9.06	9.30	ChEMBL

Showing 1 to 1 of 1 entry

TD-8954

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	Yes

Clinical Trials

Phase I 0

Phase II 0

Phase III 0

Approved No

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids DrugBank GPCRdb

Compound is not listed as a drug.