CHEMBL147186


SMILES CC(C)N(C(=O)CN1C(=O)C(NC(=O)Nc2cccc(C(=O)O)c2)C(=O)N(c2ccccc2)c2ccccc21)c1ccccc1
InChIKey CABBMMXFOOZVMS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 8
Molecular weight (Da) 605.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCK2 GASR Human Cholecystokinin A pKi 8.0 8.0 8.0 ChEMBL
CCK1 CCKAR Human Cholecystokinin A pKi 6.9 6.9 6.9 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCK1 CCKAR Guinea pig Cholecystokinin A pEC50 7.4 7.4 7.4 ChEMBL
CCK2 GASR Human Cholecystokinin A pIC50 8.0 8.0 8.0 ChEMBL
CCK1 CCKAR Human Cholecystokinin A pIC50 6.9 6.9 6.9 ChEMBL