GPCRdb

VNA932

Agent/drug
Bioactivity

VNA932

SMILES	Cc1ccn(-c2ccc(C(=O)N3Cc4cccn4Cc4ccccc43)c(Cl)c2)n1
InChIKey	JXKQHDZUZGKDGO-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	0
Rotatable bonds	2
Molecular weight (Da)	402.1

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

OT	OXYR	Human	Vasopressin and oxytocin	A	pKi	6.70	6.77	6.90	ChEMBL
V_1A	V1AR	Human	Vasopressin and oxytocin	A	pKi	6.33	6.42	6.46	ChEMBL
V₂	V2R	Human	Vasopressin and oxytocin	A	pKi	7.30	7.33	7.40	ChEMBL

Showing 1 to 3 of 3 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

OT	OXYR	Rat	Vasopressin and oxytocin	A	pIC50	7.26	7.26	7.26	ChEMBL
OT	OXYR	Human	Vasopressin and oxytocin	A	pIC50	6.45	6.45	6.45	ChEMBL
OT	OXYR	Human	Vasopressin and oxytocin	A	pEC50	6.90	6.90	6.90	ChEMBL
V_1A	V1AR	Human	Vasopressin and oxytocin	A	pIC50	5.78	6.00	6.11	ChEMBL
V_1A	V1AR	Human	Vasopressin and oxytocin	A	pEC50	6.33	6.33	6.33	ChEMBL
V₂	V2R	Human	Vasopressin and oxytocin	A	pIC50	7.10	7.10	7.10	Guide to Pharmacology
V₂	V2R	Human	Vasopressin and oxytocin	A	pIC50	7.09	7.09	7.10	ChEMBL
V₂	V2R	Human	Vasopressin and oxytocin	A	pEC50	7.40	8.56	9.15	ChEMBL

Showing 1 to 8 of 8 entries

VNA932

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids GPCRdb

Compound is not listed as a drug.