GPCRdb

VUF 8430

Agent/drug
Bioactivity

VUF 8430

SMILES	N=C(N)SCCN=C(N)N
InChIKey	GSYGTVNTZHFQQH-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	4
Rotatable bonds	3
Molecular weight (Da)	161.1

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids GPCRdb
Ligand site mutations	H₄

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

H₃	HRH3	Human	Histamine	A	pKi	6.00	6.17	6.50	ChEMBL
H₄	HRH4	Human	Histamine	A	pKi	7.50	7.50	7.50	Guide to Pharmacology
H₄	HRH4	Human	Histamine	A	pKi	7.50	7.53	7.60	ChEMBL

Showing 1 to 3 of 3 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

H₃	HRH3	Human	Histamine	A	pEC50	6.50	6.50	6.50	ChEMBL
H₄	HRH4	Mouse	Histamine	A	pEC50	5.06	5.06	5.06	ChEMBL
H₄	HRH4	Rat	Histamine	A	pEC50	4.47	4.47	4.47	ChEMBL
H₄	HRH4	Human	Histamine	A	pEC50	7.30	7.34	7.42	ChEMBL

Showing 1 to 4 of 4 entries

VUF 8430

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids GPCRdb
Ligand site mutations	H₄

Compound is not listed as a drug.