zafirlukast
zafirlukast
SMILES | COc1cc(ccc1Cc1cn(c2c1cc(cc2)NC(=O)OC1CCCC1)C)C(=O)NS(=O)(=O)c1ccccc1C |
InChIKey | YEEZWCHGZNKEEK-UHFFFAOYSA-N |
Chemical Properties
Hydrogen bond acceptors | 7 |
Hydrogen bond donors | 2 |
Rotatable bonds | 8 |
Molecular weight (Da) | 575.2 |
Database connections
Structure pdb | 6RZ5 |
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
Protein | Gene | Species | Family | Class | Type | Min | Avg | Max | Database |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
Protein | Gene | Species | Family | Class | Type | Min | Avg | Max | Database |
zafirlukast
Drug properties
Molecular type | Small molecule |
Physiological/Surrogate | Surrogate |
Approved drug | Yes |
Clinical Trials
Phase I
0
Phase II
1
Phase III
0
Approved
Yes
Database connections
Structure pdb | 6RZ5 |
Sankey plot
Drug Information
Target | Disease | Phase | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Gene | Protein | Receptor family | Ligand type | Class | Indication name | ICD11 | ATC | Association score | Phase | Approved |