CHEMBL144151


SMILES N[C@@](CC1c2ccccc2Oc2ccccc21)(C(=O)O)[C@H]1C[C@@H]1C(=O)O
InChIKey VLZBRVJVCCNPRJ-ZQGRQUNCSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 5
Molecular weight (Da) 353.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Rat Metabotropic glutamate C pKi 8.39 8.39 8.39 ChEMBL
mGlu2 GRM2 Rat Metabotropic glutamate C pKi 8.43 8.43 8.43 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Human Metabotropic glutamate C pIC50 7.8 7.8 7.8 ChEMBL
mGlu3 GRM3 Rat Metabotropic glutamate C pEC50 7.0 7.0 7.0 ChEMBL
mGlu2 GRM2 Rat Metabotropic glutamate C pEC50 7.3 7.3 7.3 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pIC50 6.7 6.7 6.7 ChEMBL