ESCITALOPRAM


SMILES CN(C)CCC[C@@]1(c2ccc(F)cc2)OCc2cc(C#N)ccc21
InChIKey WSEQXVZVJXJVFP-FQEVSTJZSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 324.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 8.25 8.25 8.25 Drug Central
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 8.23 8.23 8.23 Drug Central
α1A ADA1A Human Adrenoceptors A pKi 8.27 8.27 8.27 Drug Central
H1 HRH1 Human Histamine A pKi 8.24 8.24 8.24 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M1 ACM1 Rat Acetylcholine (muscarinic) A Potency 5.0 5.1 5.2 ChEMBL