GPCRdb

ESCITALOPRAM

Agent/drug
Bioactivity

ESCITALOPRAM

SMILES	CN(C)CCC[C@@]1(c2ccc(F)cc2)OCc2cc(C#N)ccc21
InChIKey	WSEQXVZVJXJVFP-FQEVSTJZSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	0
Rotatable bonds	5
Molecular weight (Da)	324.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

α_1A	ADA1A	Human	Adrenoceptors	A	pKi	8.27	8.27	8.27	Drug Central
5-HT_2C	5HT2C	Human	5-Hydroxytryptamine	A	pKi	8.25	8.25	8.25	Drug Central
H₁	HRH1	Human	Histamine	A	pKi	8.24	8.24	8.24	Drug Central
M₁	ACM1	Human	Acetylcholine (muscarinic)	A	pKi	8.23	8.23	8.23	Drug Central

Showing 1 to 4 of 4 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

M₁	ACM1	Rat	Acetylcholine (muscarinic)	A	Potency	5.00	5.10	5.20	ChEMBL

Showing 1 to 1 of 1 entry

ESCITALOPRAM

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.