GPCRdb

2-(3-bromophenyl)histamine

Agent/drug
Bioactivity

2-(3-bromophenyl)histamine

SMILES	NCCc1cnc(-c2cccc(Br)c2)[nH]1
InChIKey	VSKJPAMQPJDPLL-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	2
Hydrogen bond donors	2
Rotatable bonds	3
Molecular weight (Da)	265.0

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids GPCRdb
Ligand site mutations	H₁

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

H₁	HRH1	Human	Histamine	A	pKi	5.70	5.70	5.70	Guide to Pharmacology
H₁	HRH1	Guinea pig	Histamine	A	pKd	8.90	9.02	9.13	ChEMBL
H₃	HRH3	Guinea pig	Histamine	A	pKd	5.20	5.20	5.20	ChEMBL
H₄	HRH4	Human	Histamine	A	pKi	6.00	6.00	6.00	Guide to Pharmacology
H₄	HRH4	Human	Histamine	A	pKi	5.80	5.80	5.80	ChEMBL

Showing 1 to 5 of 5 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

H₁	HRH1	Human	Histamine	A	pEC50	6.70	6.70	6.70	ChEMBL
H₄	HRH4	Human	Histamine	A	pEC50	5.00	5.00	5.00	ChEMBL

Showing 1 to 2 of 2 entries

2-(3-bromophenyl)histamine

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV 0

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids GPCRdb
Ligand site mutations	H₁

Compound is not listed as a drug.