CHEMBL146483


SMILES CC(=O)Nc1ccc([C@H](C)NCC2CCN(CCCc3c[nH]c4ccc(-n5cnnc5)cc34)CC2)cc1
InChIKey MKWFGBIRLNBEPK-NRFANRHFSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 10
Molecular weight (Da) 499.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pIC50 8.03 8.03 8.03 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pEC50 8.52 8.52 8.52 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pIC50 9.22 9.22 9.22 ChEMBL