CHEMBL146729


SMILES c1cc(CNC2CCN(CCCc3c[nH]c4ccc(-n5cnnc5)cc34)CC2)ccn1
InChIKey QWPVIERGHLZGFT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 8
Molecular weight (Da) 415.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pIC50 6.85 6.85 6.85 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pEC50 7.89 7.89 7.89 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pIC50 7.62 7.62 7.62 ChEMBL