CHEMBL147071


SMILES COc1ccc(NC(=O)c2ccc(-c3ccc(C(N)=O)cc3C)cc2)cc1N1CCN(C)CC1
InChIKey VFXRXIHKXXMGNA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 458.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Rat 5-Hydroxytryptamine A pIC50 8.89 8.89 8.89 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pIC50 8.0 8.0 8.0 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pIC50 7.24 7.24 7.24 ChEMBL