CHEMBL147677


SMILES NCCc1c[nH]c2ccc(OCCNC(=O)NCCOc3ccc4[nH]cc(CCN)c4c3)cc12
InChIKey XUSDUSKCHYLHLE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 6
Rotatable bonds 12
Molecular weight (Da) 464.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 9.7 9.7 9.7 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 9.4 9.4 9.4 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.66 8.66 8.66 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pEC50 8.8 8.8 8.8 ChEMBL