CHEMBL105515


SMILES CC1CCCC(C)N1CCCOc1ccc(-c2ccc(C#N)cc2)cc1
InChIKey RGULNTQENHHTRC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 348.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Rat Histamine A pKi 7.79 7.79 7.79 ChEMBL
H2 HRH2 Human Histamine A pKi 4.62 4.62 4.62 ChEMBL
H1 HRH1 Human Histamine A pKi 5.4 5.4 5.4 ChEMBL
H3 HRH3 Human Histamine A pKi 8.67 8.67 8.67 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database