CHEMBL106158


SMILES C/N=C(\NC#N)NC[C@@H]1CC[C@H](c2c[nH]cn2)O1
InChIKey CCOQWVUQXNRKKP-WCBMZHEXSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 3
Molecular weight (Da) 248.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKi 6.65 6.68 6.7 ChEMBL
H3 HRH3 Human Histamine A pKi 5.15 5.18 5.2 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pEC50 6.65 6.68 6.7 ChEMBL
H3 HRH3 Human Histamine A pEC50 4.99 5.0 5.0 ChEMBL