CHEMBL1632414


SMILES CN1CCC(/C(=N/O)c2nc3cc(Cl)ccc3[nH]2)CC1
InChIKey ZKDRIYJOVIMHFC-AQTBWJFISA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 292.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Mouse Histamine A pKi 8.1 8.1 8.1 ChEMBL
H4 HRH4 Rat Histamine A pKi 7.8 7.8 7.8 ChEMBL
H4 HRH4 Human Histamine A pKi 7.8 7.8 7.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Mouse Histamine A pEC50 7.2 7.2 7.2 ChEMBL
H4 HRH4 Rat Histamine A pEC50 6.7 6.7 6.7 ChEMBL
H4 HRH4 Human Histamine A pEC50 7.1 7.1 7.1 ChEMBL