CHEMBL1643779


SMILES CN([C@@H]1CCc2c(CC(=O)O)c3cc(F)c(F)cc3n2C1)S(=O)(=O)c1ccc(F)cc1
InChIKey HQGWUEBEBDOPRO-CYBMUJFWSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 452.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
DP2 PD2R2 Human Prostanoid A pKi 8.6 8.6 8.6 ChEMBL
DP1 PD2R Human Prostanoid A pKi 6.92 6.92 6.92 ChEMBL
TP TA2R Human Prostanoid A pKi 6.14 6.14 6.14 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
DP2 PD2R2 Human Prostanoid A pIC50 8.42 8.42 8.42 ChEMBL