GPCRdb

CHEMBL1078207

Agent/drug
Bioactivity

CHEMBL1078207

SMILES	O=S(=O)(Nc1ccc2c(c1)CCN(Cc1cc[nH]n1)CC2)c1ccc(-c2ccccc2)cc1
InChIKey	GSIRAOVJCFHRIN-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	2
Rotatable bonds	6
Molecular weight (Da)	458.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT₆	5HT6R	Human	5-Hydroxytryptamine	A	pKi	6.90	6.90	6.90	ChEMBL
D₂	DRD2	Human	Dopamine	A	pKi	6.20	6.20	6.20	ChEMBL
D₃	DRD3	Human	Dopamine	A	pKi	7.50	7.50	7.50	ChEMBL

Showing 1 to 3 of 3 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

ghrelin	GHSR	Human	Ghrelin	A	pEC50	5.80	5.80	5.80	ChEMBL
motilin	MTLR	Human	Motilin	A	pEC50	8.00	8.00	8.00	ChEMBL

Showing 1 to 2 of 2 entries

CHEMBL1078207

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.