GPCRdb

CHEMBL1078208

Agent/drug
Bioactivity

CHEMBL1078208

SMILES	CC(C)Oc1ccc(S(=O)(=O)Nc2ccc3c(c2)CCN(Cc2cc[nH]n2)CC3)cc1
InChIKey	GHHKXCCOHHVPRP-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	5
Hydrogen bond donors	2
Rotatable bonds	7
Molecular weight (Da)	440.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT₆	5HT6R	Human	5-Hydroxytryptamine	A	pKi	6.70	6.70	6.70	ChEMBL
D₂	DRD2	Human	Dopamine	A	pKi	6.20	6.20	6.20	ChEMBL
D₃	DRD3	Human	Dopamine	A	pKi	7.70	7.70	7.70	ChEMBL

Showing 1 to 3 of 3 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

ghrelin	GHSR	Human	Ghrelin	A	pEC50	6.80	6.80	6.80	ChEMBL
motilin	MTLR	Human	Motilin	A	pEC50	8.40	8.40	8.40	ChEMBL

Showing 1 to 2 of 2 entries

CHEMBL1078208

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.