GPCRdb

balovaptan

Agent/drug
Bioactivity

balovaptan

SMILES	CN1Cc2cc(Cl)ccc2-n2c(nnc2[C@H]2CC[C@H](Oc3ccccn3)CC2)C1
InChIKey	GMPZPHGHNDMRKL-RZDIXWSQSA-N

Chemical Properties

Hydrogen bond acceptors	6
Hydrogen bond donors	0
Rotatable bonds	3
Molecular weight (Da)	409.2

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids DrugBank GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_2B	5HT2B	Human	5-Hydroxytryptamine	A	pKd	11.57	11.57	11.57	Guide to Pharmacology
OT	OXYR	Human	Vasopressin and oxytocin	A	pKi	5.15	5.15	5.15	Guide to Pharmacology
V_1A	V1AR	Human	Vasopressin and oxytocin	A	pKd	8.59	8.59	8.59	Guide to Pharmacology
V_1A	V1AR	Human	Vasopressin and oxytocin	A	pKi	9.15	9.15	9.15	ChEMBL
V₂	V2R	Human	Vasopressin and oxytocin	A	pKd	5.00	5.00	5.00	Guide to Pharmacology
V₂	V2R	Human	Vasopressin and oxytocin	A	pKi	5.92	5.92	5.92	ChEMBL

Showing 1 to 6 of 6 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

V_1A	V1AR	Human	Vasopressin and oxytocin	A	pIC50	8.52	8.52	8.52	ChEMBL

Showing 1 to 1 of 1 entry

balovaptan

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	Yes

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids DrugBank GPCRdb

Compound is not listed as a drug.