CHEMBL159483


SMILES O=C1N[C@@H](Cc2ccc3[nH]cc(CCN4CC[C@@H](CNCc5ccccc5)C4)c3c2)CO1
InChIKey DZFRWAZJFQMVAM-GMAHTHKFSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 9
Molecular weight (Da) 432.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pIC50 7.31 7.31 7.31 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pIC50 9.46 9.46 9.46 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pEC50 8.77 8.77 8.77 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pIC50 7.77 7.77 7.77 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 5.52 5.52 5.52 ChEMBL