CHEMBL160070


SMILES C[C@H](NC[C@@H]1CCN(CCc2c[nH]c3ccc(C[C@H]4COC(=O)N4)cc23)C1)c1ccccc1
InChIKey IKUAJUBZHRXQPW-PTLVVNQVSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 9
Molecular weight (Da) 446.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pIC50 7.3 7.3 7.31 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pIC50 9.52 9.52 9.52 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pEC50 9.3 9.3 9.3 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 5.66 5.66 5.66 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pIC50 8.06 8.06 8.06 ChEMBL