CHEMBL1767137


SMILES COc1ccc(Cc2nn(C[C@H]3CCCN3C)c(=O)c3ccccc23)cc1
InChIKey MBVVVQZOMZFVJF-QGZVFWFLSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 363.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A ADA1A Human Adrenoceptors A pKi 6.9 6.9 6.9 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 6.8 6.8 6.8 ChEMBL
H1 HRH1 Human Histamine A pKi 10.0 10.0 10.0 ChEMBL
H3 HRH3 Human Histamine A pKi 7.1 7.1 7.1 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database