GPCRdb

CHEMBL1765633

Agent/drug
Bioactivity

CHEMBL1765633

SMILES	CCCN(CCCCNC(=O)c1ccc(-c2ccccc2)cc1)[C@H]1CCn2nccc2C1
InChIKey	UTFOVXIJDJSMKK-VWLOTQADSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	1
Rotatable bonds	10
Molecular weight (Da)	430.3

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₂	DRD2	Human	Dopamine	A	pKi	8.28	8.64	9.00	ChEMBL
D₃	DRD3	Human	Dopamine	A	pKi	6.07	8.89	10.57	ChEMBL

Showing 1 to 2 of 2 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₂	DRD2	Human	Dopamine	A	pEC50	6.43	7.56	9.29	ChEMBL
D₃	DRD3	Human	Dopamine	A	pEC50	10.25	10.25	10.25	ChEMBL

Showing 1 to 2 of 2 entries

CHEMBL1765633

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.